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In this cult horror classic Boris Karloff is mad scientist Dr. Adrian, a man who becomes obsessed with curing paralysis. Desperately trying to cure a crippled young woman he discovers that he needs human spinal fluid for his vaccine - but how to get it? When an ape trainer at a local circus is badly mauled, the doctor allows him to die so that he can tap his spine. But then the gorilla escapes and goes on a killing spree terrorizing the small town.